Retina/Vitreous

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Patent granted for method of use of Acucela’s Stargardt disease treatment

September 14, 2017

The U.S. Patent and Trademark Office granted U.S. Patent No. 9,737,496 B2 to Acucela for method of use of its Stargardt disease treatment emixustat hydrochloride or a “broad number of related compounds,” according to a company press release.

Emixustat was granted orphan drug designation in January for the treatment of Stargardt disease, which affects fewer than 40,000 patients in the United States.

Lampalizumab trial for geographic atrophy fails to meet endpoint

September 12, 2017
A phase 3 study of lampalizumab for geographic atrophy failed to meet its primary endpoint of reducing mean change in lesion area, Roche announced in a press release…

Solar eclipse, ASRS meeting top retina news

September 11, 2017
News of the solar eclipse that crossed the United States led retina-based ophthalmology news in the month of August, with coverage from the American Society of Retina…
In the Journals

Mobility test tracks vision changes in inherited retinal dystrophies

September 8, 2017
A novel multi-luminance mobility test accurately distinguished normal-sighted subjects from visually impaired subjects with inherited retinal dystrophies and tracked…
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Clinical Science Imaging

Optic Disc and Retinal Nerve Fiber Layer Parameters of Eyes With Keratoconus

Ophthalmic Surgery, Lasers and Imaging Retina, September 2012, Volume 43 Issue 5
To evaluate optic nerve head (ONH) characteristics and retinal nerve fiber layer (RNFL) thickness measurements in…
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CME

Wet Macular Degeneration: A Review of Pivotal Clinical Trials

This activity is supported by educational grants from Allergan, Inc.; Genentech, Inc.; and Regeneron Pharmaceuticals, Inc.

The advent of intravitreal therapies to treat retinal diseases has revolutionized the management of retinal pathology…
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Resource Centers
American Society of Retina Specialists Meeting

American Society of Retina Specialists Meeting

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Meeting News

VIDEO: Sirolimus reduces vitreous haze in patients with posterior uveitis

May 14, 2017
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Patent granted for method of use of Acucela’s Stargardt disease treatment

September 14, 2017
The U.S. Patent and Trademark Office granted U.S. Patent No. 9,737,496 B2 to Acucela for method of use of its Stargardt disease treatment emixustat…

Lampalizumab trial for geographic atrophy fails to meet endpoint

September 12, 2017
A phase 3 study of lampalizumab for geographic atrophy failed to meet its primary endpoint of reducing mean change in lesion area, Roche announced in…

Solar eclipse, ASRS meeting top retina news

September 11, 2017
News of the solar eclipse that crossed the United States led retina-based ophthalmology news in the month of August, with coverage from the American…

In the Journals

Mobility test tracks vision changes in inherited retinal dystrophies

September 8, 2017
A novel multi-luminance mobility test accurately distinguished normal-sighted subjects from visually impaired subjects with inherited retinal…

Usher syndrome candidate receives orphan drug designation

September 5, 2017
The FDA and the European Medicines Agency have granted orphan drug designation to QRX-421, an investigational drug for Usher syndrome, according to a…

PUBLICATION EXCLUSIVE: Man presents with blurry vision and floaters after cataract surgery

September 2, 2017
A 73-year-old Caucasian man was referred to the uveitis service at Tufts Medical Center for persistent iritis of the right eye associated with cloudy…

In the Journals

Phenotypic characteristics associated with CFH variants

September 1, 2017
Genetic testing should be considered for patients with age-related macular degeneration and certain phenotypic characteristics, such as an extensive…

Grand Rounds at the New England Eye Center

Young woman presents with blurred vision, loss of visual fields

Ocular Surgery News U.S. Edition, September 10, 2017
Omar A.W. Dajani, MD; Sarkis Soukiasian, MD
A 19-year-old Hispanic woman with no significant medical or ocular history was referred to the department of ophthalmology at the Lahey Clinic for…

In the Journals

Extension study highlights long-term outcomes of aflibercept in DME

August 29, 2017
Two-year results of the ENDURANCE phase 4 extension study, evaluating the long-term efficacy and safety of intravitreal aflibercept for the treatment…

Meeting News

Novel integrin peptide therapy yields visual acuity gains on par with Avastin for DME

August 25, 2017
BOSTON — Sequential therapy with 1 mg ALG-1001 yielded equivalent visual acuity gains as treatment with bevacizumab monotherapy in patients…

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