Eric D. Donnenfeld
SAN DIEGO — Early study results show the Juvene IOL provides a range of accommodative vision that is better than what is provided by extended depth of focus lenses, Eric D. Donnenfeld, MD, said at the American Society of Cataract and Refractive Surgery annual meeting.
One-month results of the Grail trial, in which 44 eyes have been implanted with the Juvene (LensGen) IOL by multiple surgeons at two international sites, show reproducible 3 D of accommodation.
“It certainly significantly outperforms our EDOF lenses today without splitting of light, and when you perform binocular surgery, the defocus curve even gets better, as you would expect,” Donnenfeld said.
Regarding visual performance, best corrected distance vision was 20/20 in 85% of eyes and better than 20/32 in 100% of eyes.
“Patients had excellent intermediate vision, and even at near at 40 cm, half the patients were able to read 20/32, again without splitting of light that you see with other multifocal and EDOF lenses,” he said.
Target achieved was close to emmetropia with a standard deviation of 0.38.
“This is attributable to the fact that there’s no deviation in the effective lens position because the base lens fills the capsular bag,” he said. The Juvene IOL is a two-piece modular construction intended for small incision implantation.
In a patient satisfaction questionnaire, patients reported no glare and no halos, while two patients reported mild monocular starbursts.
“We have previous generations of information. We’ve been doing this surgery now for 4 years,” Donnenfeld said. Based on that prior data, there have been no cases of posterior capsular opacification.
“I’m excited about the early results,” Donnenfeld said. “I think the Juvene IOL is well tolerated, you can insert it through a very small incision, it’s been proven to reduce posterior capsular opacification and vitreous traction, it fills the capsular bag and has an exchangeable platform.”
The final lens design for use in trials will be presented to the FDA this year, Donnenfeld said.
“The holy grail for all of us is a true accommodating IOL that really does not split light and gives us the ability to see distance and near,” he said. – by Patricia Nale, ELS
Reference: Donnenfeld ED. A new modular, curvature-changing, fluid-optic intraocular lens. Presented at: American Society of Cataract and Refractive Surgery annual meeting; May 3-7, 2019; San Diego.
Disclosure: Donnenfeld reports he is a consultant for LensGen.