LASIK with a new-generation excimer laser and optimized ablation profiles corrected high mixed astigmatism, according to a study.
The retrospective study included 52 eyes of 36 patients who had more than 3 D of primary mixed astigmatism.
Investigators used the sixth-generation Amaris excimer laser (Schwind eye-tech solutions) to perform ablation based on optimized aspherical aberration-free profiles calculated with the Ork-Cam (Schwind). Cyclotorsion control and eye tracking software were also used.
LASIK flaps were created with the IntraLase femtosecond laser (Abbott Medical Optics).
At 3 months, there was a statistically significant reduction in refractive sphere and cylinder and improvement in logMAR uncorrected distance visual acuity (both P = .001). Best corrected distance visual acuity was unchanged in 31 eyes; three eyes gained two lines, seven eyes gained one line, eight eyes lost one line, and three eyes lost two lines.
Spherical equivalent was within 0.5 D of targeted refraction in 14 eyes and within 1 D in 34 eyes.
Re-treatment was required in seven eyes.
Postoperative corrected distance visual acuity was 0.3 or better in all eyes.
There was a statistically significant increase in higher-order aberrations attributed to an increase in primary spherical aberrations (both P = .002), the authors said.