Journal of Refractive Surgery

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Original Article 

Factors Affecting Contrast Sensitivity With the Artisan Phakic Intraocular Lens for High Myopia

Takefumi Yamaguchi, MD; Kazuno Negishi, MD; Naoko Kato, MD; Hiroyuki Arai, MD; Ikuko Toda, MD; Kazuo Tsubota, MD

  • Journal of Refractive Surgery. 2009;25(1):25-32
  • Posted January 1, 2009

Abstract

PURPOSE

To evaluate the factors affecting postoperative visual function in eyes with Artisan phakic intraocular lenses (PIOLs).

METHODS

This study examined a retrospective noncomparative case series. Phakic IOLs were implanted in 60 eyes of 36 patients with high myopia. Contrast sensitivity for spatial frequencies of 1.1, 1.7, 2.6, 4.2, 6.6, and 10.4 cycles per degree with and without glare and wavefront aberrations were measured before and 3 months after surgery. The area under the log contrast sensitivity function (AULCSF) was calculated from the contrast sensitivity. Stepwise regression analysis was used to assess the factors that affected the postoperative AULCSF.

RESULTS

No significant difference was noted between the preoperative AULCSF without glare and the postoperative AULCSF without glare (P=.886). The mean AULCSF with glare improved significantly after surgery (P=.018). The variables affecting the postoperative AULCSF without glare were axial length (partial regression coefficient B=–0.101, P=.0002) and age (B=–0.008, P=.0063). The variables affecting the postoperative AULCSF with glare were axial length (B=–0.127, P<.0001) and age (B=–0.012, P=.0294). The preoperative refraction showed multicollinearity with the axial length, and coma-like aberration and spherical aberration showed multicollinearity with age.

CONCLUSIONS

Contrast sensitivity without glare was the same before and after surgery and contrast sensitivity with glare improved after surgery. Longer axial length and older age predispose patients to degradation of the postoperative visual function in eyes with Artisan PIOLs. [J Refract Surg. 2009;25:25-32.]

AUTHORS

From the Department of Ophthalmology, Keio University School of Medicine (Yamaguchi, Negishi, Kato, Toda, Tsubota), and Minamiaoyama Eye Clinic (Kato, Arai, Toda), Tokyo, Japan.

The authors have no financial or proprietary interest in the materials presented herein.

Correspondence: Kazuno Negishi, MD, Dept of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan. Tel/Fax: 81 3 3353 1211; E-mail: fwic7788@mb.infoweb.ne.jp

Received: July 23, 2007

Accepted: January 16, 2008

Posted online: May 30, 2008

Abstract

PURPOSE

To evaluate the factors affecting postoperative visual function in eyes with Artisan phakic intraocular lenses (PIOLs).

METHODS

This study examined a retrospective noncomparative case series. Phakic IOLs were implanted in 60 eyes of 36 patients with high myopia. Contrast sensitivity for spatial frequencies of 1.1, 1.7, 2.6, 4.2, 6.6, and 10.4 cycles per degree with and without glare and wavefront aberrations were measured before and 3 months after surgery. The area under the log contrast sensitivity function (AULCSF) was calculated from the contrast sensitivity. Stepwise regression analysis was used to assess the factors that affected the postoperative AULCSF.

RESULTS

No significant difference was noted between the preoperative AULCSF without glare and the postoperative AULCSF without glare (P=.886). The mean AULCSF with glare improved significantly after surgery (P=.018). The variables affecting the postoperative AULCSF without glare were axial length (partial regression coefficient B=–0.101, P=.0002) and age (B=–0.008, P=.0063). The variables affecting the postoperative AULCSF with glare were axial length (B=–0.127, P<.0001) and age (B=–0.012, P=.0294). The preoperative refraction showed multicollinearity with the axial length, and coma-like aberration and spherical aberration showed multicollinearity with age.

CONCLUSIONS

Contrast sensitivity without glare was the same before and after surgery and contrast sensitivity with glare improved after surgery. Longer axial length and older age predispose patients to degradation of the postoperative visual function in eyes with Artisan PIOLs. [J Refract Surg. 2009;25:25-32.]

AUTHORS

From the Department of Ophthalmology, Keio University School of Medicine (Yamaguchi, Negishi, Kato, Toda, Tsubota), and Minamiaoyama Eye Clinic (Kato, Arai, Toda), Tokyo, Japan.

The authors have no financial or proprietary interest in the materials presented herein.

Correspondence: Kazuno Negishi, MD, Dept of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan. Tel/Fax: 81 3 3353 1211; E-mail: fwic7788@mb.infoweb.ne.jp

Received: July 23, 2007

Accepted: January 16, 2008

Posted online: May 30, 2008

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