Systemic oral propranolol was effective in treating infantile capillary hemangiomas of the eyelid with minimal risk of complications, according to a study.
In a prospective, interventional case series, 14 patients with a mean age of 20.85 months who had infantile capillary hemangiomas of the eyelid underwent oral treatment with systemic propranolol.
Mean administration of treatment was 2.5 months. Treatment was discontinued after 2 months in one case due to hypotension and after 3 months in another case due to allergy. Mean follow-up was 10.64 months.
Ten patients younger than 1 year showed full regression of the lesion with treatment. Two patients older than 5 years significantly benefited from treatment but did not show full regression.
Four patients had existing amblyogenic astigmatism, which decreased from 1.25 D before treatment to 0.25 D at final visit with no observed recurrence after treatment.
The study authors said that 4 months of treatment appears to be ideal for the highest effectiveness.