An increase to 6 hours of daily patching for residual amblyopia yielded greater improvement in visual acuity than continuing with 2 hours of daily patching.
A prospective, randomized, multicenter study included 169 children between the ages of 3 years up to 8 years with stable residual amblyopia after 12 weeks of 2-hour daily patching.
Patients were randomly selected to either continue 2 hours of daily patching or increase patching to 6 hours daily.
Mean baseline logMAR best corrected visual acuity was 0.44 for all subjects.
After 10 weeks, visual acuity in the amblyopic eye improved an average of 0.5 lines in the 2-hour group and an average of 1.2 lines in the 6-hour group (P = .002). The 6-hour group yielded improvement of two lines or greater in 40% of patients compared with 18% of patients in the 2-hour group; the difference was statistically significant (P = .003).
“If significant amblyopia persists, we now know that it is reasonable to increase the dose of patching therapy,” the study authors said.
Disclosure: The study authors have no relevant financial disclosures.