The authors describe two cases of bilateral simultaneous stage 1 macular hole diagnosed via optical coherence tomography (OCT). Vitreomacular traction, foveal pseudo cysts, and outer retinal changes were present initially. Resolution of the foveal pseudo cysts and outer retinal changes occurred in cases where a complete posterior vitreous detachment was noted. The initial step in the pathogenesis of macular holes is “traction” from the detaching posterior hyaloid. However, there are missing links in the exact inciting events and in the progression of the disease. The development of bilateral stage 1 macular holes simultaneously is unique and interesting because an unknown common inciting factor might be at play in these cases.
From New England Eye Center, Tufts Medical Center, Boston, Massachusetts.
Supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, New York, to the New England Eye Center/Department of Ophthalmology-Tufts University School of Medicine; NIH contracts RO1-EY11289-23, R01-EY13178-07, R01-EY013516-07; Air Force Office of Scientific Research FA9550-07-1-0101 and FA9550-07-1-0014; and the Massachusetts Lions Eye Research Fund.
Dr. Duker receives research support from Carl Zeiss Meditec, Inc., Optovue, Inc., and Topcon Medical Systems, Inc. The remaining authors have no financial or proprietary interest in the materials presented herein.
Dr. Duker did not participate in the editorial review of this manuscript.
Address correspondence to Jay S. Duker, MD, New England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111. E-mail: Jduker@tuftsmedicalcenter.org
Received: May 31, 2012
Accepted: August 09, 2012
Posted Online: September 27, 2012