Ultra-widefield imaging was found to have “moderate to substantial agreement” with ETDRS 7-field imaging to determine the severity of diabetic retinopathy.
The cross-sectional study included 764 eyes. Both ETDRS 7-field and ultra-widefield images were evaluated by trained graders to find the agreement between the ultra-widefield images, ultra-widefield images masked to include only the ETDRS 7-field area and ETDRS 7-field images.
Researchers obtained modified ETDRS 7-field images using the Diabetic Retinopathy Clinical Research Network acquisition protocol and ultra-widefield images using the Optos 200Tx system.
In total, 737 gradable eyes contained the seven fields after adjudication on both ETDRS 7-field and ultra-widefield images. After adjudication, diabetic retinopathy severity between the images matched exactly in 435 eyes and were within one severity grade in 714 eyes.
Among adjudicated images, the ability of ETDRS and ultra-widefield masked images to detect retinopathy severity was similar in 59 eyes, ultra-widefield masked images were considered more accurate in 31 eyes, and ETDRS 7-field images were considered more accurate in 22 eyes.
“The identification of a subset of patients at greatly increased risk of experiencing DR progression and onset of proliferative DR that cannot be assessed by ETDRS 7-field imaging would have important implications for the evaluation and care of diabetic eye
disease,” the study authors wrote. – by Robert Linnehan
Disclosures: Aiello reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures.