In the Journals

Ab interno trabeculotomy with Trab360 effective in childhood glaucomas

Two-thirds of eyes with childhood glaucomas that underwent ab interno trabeculotomy with the Trab360 device experienced postoperative IOP of 24 mm Hg or less with no additional surgeries, according to a study.

“We concluded that single-incision ab interno trabeculotomy is effective and safe for treating pediatric glaucomas, especially primary congenital glaucoma. Good surgical technique and caution in high-risk angles is imperative to avoid cyclodialysis,” study co-author Raymond G. Areaux Jr., MD, told Healio/OSN.

The multicenter retrospective interventional case series included 46 eyes with childhood glaucoma that underwent trabeculotomy using the Trab360 device (Sight Sciences) by one of four surgeons at four academic medical centers with at least 3 months of follow-up.

Mean preoperative IOP was 30.9 mm Hg, and mean follow-up was 16.2 months.

Two-thirds of eyes with childhood glaucomas that underwent ab interno trabeculotomy with the Trab360 device experienced postoperative IOP of 24 mm Hg or less with no additional surgeries.

Surgical success, defined as postoperative IOP of 24 mm Hg or less, with or without medications, with no additional IOP-lowering surgeries, was achieved in 67.4% of all eyes; in 40 eyes for which Trab360 was the first glaucoma surgery, success was achieved in 70% of cases. Surgery was successful in 81% of 21 eyes with primary congenital glaucoma. Also, in 18 eyes with primary congenital glaucoma first treated with Trab360, the success rate was 83.3%.

In the subgroup of successful eyes, the mean IOP decrease was 13.65 mm Hg with a mean 1.3 glaucoma medications used at a mean follow-up of 15.3 months.

Fifteen eyes failed because they needed additional IOP-lowering surgery for uncontrolled glaucoma or surgery due to complications. Two eyes experienced hypotony due to intraoperative cyclodialysis cleft formation. – by Robert Linnehan

Disclosures: The authors report no relevant financial disclosures.

Two-thirds of eyes with childhood glaucomas that underwent ab interno trabeculotomy with the Trab360 device experienced postoperative IOP of 24 mm Hg or less with no additional surgeries, according to a study.

“We concluded that single-incision ab interno trabeculotomy is effective and safe for treating pediatric glaucomas, especially primary congenital glaucoma. Good surgical technique and caution in high-risk angles is imperative to avoid cyclodialysis,” study co-author Raymond G. Areaux Jr., MD, told Healio/OSN.

The multicenter retrospective interventional case series included 46 eyes with childhood glaucoma that underwent trabeculotomy using the Trab360 device (Sight Sciences) by one of four surgeons at four academic medical centers with at least 3 months of follow-up.

Mean preoperative IOP was 30.9 mm Hg, and mean follow-up was 16.2 months.

Two-thirds of eyes with childhood glaucomas that underwent ab interno trabeculotomy with the Trab360 device experienced postoperative IOP of 24 mm Hg or less with no additional surgeries.

Surgical success, defined as postoperative IOP of 24 mm Hg or less, with or without medications, with no additional IOP-lowering surgeries, was achieved in 67.4% of all eyes; in 40 eyes for which Trab360 was the first glaucoma surgery, success was achieved in 70% of cases. Surgery was successful in 81% of 21 eyes with primary congenital glaucoma. Also, in 18 eyes with primary congenital glaucoma first treated with Trab360, the success rate was 83.3%.

In the subgroup of successful eyes, the mean IOP decrease was 13.65 mm Hg with a mean 1.3 glaucoma medications used at a mean follow-up of 15.3 months.

Fifteen eyes failed because they needed additional IOP-lowering surgery for uncontrolled glaucoma or surgery due to complications. Two eyes experienced hypotony due to intraoperative cyclodialysis cleft formation. – by Robert Linnehan

Disclosures: The authors report no relevant financial disclosures.