In European-derived populations, primary angle-closure glaucoma is increasingly prevalent, according to a study.
The literature review examined more than 40 years of population studies on primary angle-closure glaucoma (PACG) to assess disease prevalence.
“PACG is more common than previously thought, and all primary glaucoma cases should be considered to be PACG until the anterior chamber angle is shown to be open on gonioscopy,” the study authors said.
A 0.4% PACG prevalence was found for the European-derived population 40 years of age or older.
Inclusion criteria were Caucasian or predominantly Caucasian population and a random sampling of participants with structural and/or functional evidence of glaucomatous optic neuropathy as defined by the International Society for Geographical and Epidemiological Ophthalmology.
“Our analysis suggests that PACG is between almost two and four times more common than previous estimates, and there are 1.6 million people in Europe, 581,000 people in the USA and 130,000 people in the U.K. with PACG today,” the authors said.
PACG may be expected to increase by 19% in the U.K., 9% in Europe and 18% in the U.S. within the next decade and by 51% in the U.K., 30% in Europe and 67% in the U.S. by 2050, according to the study.