Patients with neovascular glaucoma who received an Ex-Press device experienced fewer complications and had similar success rates compared with patients who were treated using trabeculectomy alone.
The retrospective observational analysis included 89 patients with neovascular glaucoma; 39 patients were treated with trabeculectomy alone and 50 patients underwent Ex-Press (Alcon) implantation.
There were fewer postoperative complications in the Ex-Press patients. Early postoperative hypotony was seen in seven eyes in the Ex-Press group compared with 14 in the trabeculectomy group (P = .016). Hyphema developed in five eyes in the Ex-Press group and 13 in the trabeculectomy group (P = .008). A shallow anterior chamber was observed in seven eyes in the trabeculectomy group compared with one in the Ex-Press group (P = .019).
Visual acuity, success rates and the number of postoperative medications were similar between the two groups of patients.
However, the researchers noted a history of vitrectomy was a risk factor for failure with the Ex-Press.
“Although no significant difference in surgical success rates between the two groups was found, implantation of an Ex-Press device was significantly advantageous for prevention of postoperative overfiltration and hyphema in patients with [neovascular glaucoma]. Ex-Press implantation may improve postoperative quality of vision in such patients. However, previous vitrectomy may have a negative effect on the surgical outcome after implantation of an Ex-Press device in patients with [neovascular glaucoma],” they wrote. – by Robert Linnehan
Disclosures: The authors report no relevant financial disclosures.