Increased excavation and neuroretinal rim thinning, particularly in the inferotemporal quadrant, were the most common features of optic disc progression, according to a study.
The study included 336 eyes of 168 patients with either high-risk ocular hypertension or early glaucoma who underwent optic disc photography through dilated pupils at baseline and annual follow-up appointments.
Optic disc progression occurred in 92 eyes after a median of 6.1 years. Eighty-nine percent of the eyes demonstrated excavation, 54% demonstrated neuroretinal rim thinning, and 16% demonstrated notching.
Two or more features of optic disc progression were present in 56% of eyes.
Thirty percent of eyes experienced progression in more than one location; progression was most common in the inferotemporal quadrant.
Early detection of optic disc changes may allow physicians to adjust patients’ therapy to avoid visual field loss and worsening of vision-associated quality of life, the study authors said.