Open-angle glaucoma was associated with an increase in stroke risk, according to findings from a 10-year retrospective study.
In the propensity score-matched cohort study, researchers selected 1,520 individuals from the Korean National Health Insurance Service database who had been diagnosed with open-angle glaucoma between January 2004 and December 2007. The study also included 7,570 controls. Both groups were tracked for stroke incidence through 2013.
Individuals in the glaucoma arm were at a higher risk for stroke compared with controls (P = .017).
Other factors that raised the stroke risk included hypertension, diabetes, chronic renal failure, atrial fibrillation, hyperlipidemia, increasing age and male gender.
In the open-angle glaucoma cohort, individuals aged 65 years or older were at greater stroke risk than younger individuals, and men were more likely than women to have a stroke.
“The association between OAG and stroke can be partially explained by common systemic risk factors for these two disorders. Hypertension and diabetes mellitus are well-known risk factors for stroke,” the researchers said. “Considering common risk factors for both diseases, control of these systemic factors may be important for patients with OAG, for the prevention of stroke development in parallel with glaucoma management.” – by Rob Volansky
Disclosures: The authors report no relevant financial disclosures.