Spectral-domain optical coherence tomography was useful for detecting progression in glaucomatous eyes through the serial measurement of parameters in circumpapillary retinal nerve fiber layer, macula and optic nerve head, according to a study.
The longitudinal, observational study included 279 eyes of 162 glaucoma patients; 63 eyes were classified as progressors and 216 as nonprogressors. Patients were followed up for a mean of 2.2 years.
The optic nerve head rim area diminished more rapidly in progressors compared with nonprogressors (−0.016 vs. −0.006 mm2/year), whereas the average and vertical cup-to-disc ratio increased more rapidly in progressors than in nonprogressors (0.004 vs. 0.002 and 0.006 vs. 0.004 per year); all changes were considered statistically significant (P < .05).
The circumpapillary retinal nerve fiber layer parameters and the macular parameters diminished more rapidly in progressors than in nonprogressors; these reductions were also statistically significant (all P < .05).
Disclosure: The study authors report no relevant financial disclosures.