SAN DIEGO — Poor air quality during forest fires in the Pacific Northwest was associated with a increase in MMP-9 improvement in patients being treated for ocular surface disease.
At the American Society for Cataract and Refractive Surgery meeting, Laura M. Periman, MD, presented results of a retrospective chart review of 72 patients who were being treated with intens pulsed light therapy for ocular surface disease.
While patients had a highly statistically significant reduction in MMP-9 throughout treatment, during times of poor air quality – as measured by local air quality index scores – MMP-9 increased.
“When we looked at the raw data...we went back and looked at the air quality index, and MMP-9 actually went up with a worsening air quality index,” Periman said.
Forest fires, being a perennial problem at the end of each summer in certain areas, such as the Pacific Northwest where Periman conducted her study, the association between the air quality and the effects it can have on eyes should be noted, she said.
“We are used to thinking about our pulmonary patients as being vulnerable, our asthmatics, etc., but I want us to start thinking about the dry eye patient as a vulnerable patient during periods of poor air quality as well,” Periman said. – by Rebecca L. Forand
Periman L. When smoke gets in your eyes: air quality index impacts on MMP-9 testing during forest fire season. Presented at: American Society of Cataract and Refractive Surgery annual meeting; May 3-7, 2019; San Diego.
Disclosure: Periman reports financial relationships with Advanced Tear Diagnostics, Allergan, Eyedetec, Johnson & Johnson, Lumenis, Olympic Ophthalmics, Quidel, ScienceBasedHealth, Shire/Takeda, Sun, TearLab and Visant.