Serum lipid concentration was found to be an independent risk factor for age-related cataract in a large cohort of Chinese subjects.
The study was carried out at a university hospital in Shanghai, China, and included 219 patients with age-related cataract and 218 control subjects. There was no significant difference in age, gender, smoking and drinking habits between the two groups, but there was a significant difference in body mass index, systolic and diastolic blood pressure, and dietary habits.
The levels of serum low-density lipoprotein cholesterol, triglyceride, cholesterol and serum apolipoprotein A were significantly higher in the cataract group than in the control group for both male and female subjects. Logistic regression analyses revealed that high low-density lipoprotein cholesterol and triglyceride were independent risk factors for age-related cataract.
The correlation between cataract and blood lipid concentration as a risk factor has been widely debated, and results were diverse and uncertain. However, in this population a clear and definite correlation was found.
The homogeneous background of the study subjects, the Chinese Han population, could be a limitation, and for this reason, results cannot be generalized. However, the authors suggested that “these findings indicate a need for health promotional activities aimed at controlling blood lipid concentration among high-risk populations.” – by Michela Cimberle
Disclosures: The authors report no relevant disclosures.