June 03, 2016
1 min read

Patients with RA had better perioperative outcomes after THA, TKA vs controls

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Patients with rheumatoid arthritis who underwent elective total hip or knee arthroplasty experienced better perioperative outcomes than patients without rheumatoid arthritis, according to results.

Using the U.S. Nationwide Inpatient Sample, researchers identified patients who underwent elective total hip arthroplasty (THA) or total knee arthroplasty (TKA) between 2000 and 2009. Researchers collected data regarding patient- and health care system-related characteristics, comorbidities, in-hospital complications and mortality, and compared in-hospital outcomes between patients with and patients without rheumatoid arthritis (RA).

Hiroyuki Yoshihara


Results showed significantly lower overall in-hospital complication rates among patients with RA who underwent THA or TKA vs. patients without RA. Researchers found patients with RA who underwent THA also experienced a lower in-hospital mortality rate compared to patients without RA. Although results showed no significant difference for the in-hospital mortality rate between patients with RA and patients without RA who underwent TKA, researchers noted the rate decreased from 0.12% to 0.05% among patients with RA.

A decreased risk of in-hospital overall complications, respiratory complications, cardiac complications, gastrointestinal complications, urinary and renal complications, and pulmonary embolism was associated with the presence of RA, according to results of a regression analysis. An increased risk of in-hospital mortality was not associated with the presence of RA, researchers found.

“Perioperative outcomes of elective THA and TKA in patients with RA were better than those in patients without RA,” Hiroyuki Yoshihara, MD, PhD, assistant professor in the Department of Orthopedic Surgery and Rehabilitation Medicine at SUNY Downstate Medical Center, told Healio.com/Rheumatology. “These results may indicate that patient selection and pre- and perioperative management of patients with RA undergoing elective THA and TKA were well conducted in the [United States] U.S. during the last decade.” – by Casey Tingle

Disclosure: Yoshihara reports no relevant financial disclosures.