American Orthopaedic Foot & Ankle Society Annual Meeting
American Orthopaedic Foot & Ankle Society Annual Meeting
October 22, 2019
1 min read

New ankle prosthesis improves patient experience with arthritis

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact

CHICAGO — Use of a new total ankle prosthesis improved the experience of patients with end-stage arthritis, according to results from a study presented at the American Orthopedic Foot & Ankle Society Annual Meeting.

Tim Daniels, M D, FRCSC, orthopedic surgeon, chief of the division of orthopedic surgery of St. Michael’s Hospital and professor at the University of Toronto, and colleagues conducted a retrospective study that examined patient outcomes after total ankle replacement using the Cadence Total Ankle System (Integra LifeSciences).

The study included 31 patients who received the prosthesis. Total ankle replacement was performed with all patients and follow-up was at least 2 years after surgery. Using the ankle osteoarthritis scale, patients’ pain and disability scores were evaluated and showed an improvement. The pain scores decreased by -20.28 ± 14.34 from the average of 47.86, and the disability scores decreased by -32.11 ± 22.70 from the average of 57.15.

According to Daniels, studies usually find cyst formation in 10% to 15% of patients, but there were no reports of cyst formation patients who underwent replacement with the studied ankle system.

“We are seeing good clinical outcomes on the patient population after a 2-year follow-up, and that’s with validated outcome scores that we’re using,” Daniels told Today in an interview. “We have seen no cyst formation, which is better than previous series on other ankles.”

According to results from the abstract, the overall quality of life, functional measures and patients’ pain from the arthritis significantly improved following surgery using the total ankle replacement system. Future research and follow-ups with these patients after 5 and 10 years are underway.

“We’re going to do a comparative study looking at equivalent patients and equipment follow-up periods that have had other types of ankle replacements just to do a comparator on this implant,” Daniels said. by Erin T. Welsh


Daniels T, et al. Abstract. Presented at: American Orthopedic Foot & Ankle Society Annual Meeting; Sept. 18, 2019; Chicago.

Disclosure: Daniels reports he is a consultant for Integra LifeSciences and receives royalties on the Cadence Total Ankle System.