August 06, 2019
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Patients may safely continue antiplatelet medication during urgent hip fracture surgery

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Patients who received antiplatelet medication and underwent urgent surgery for hip fractures were not significantly different than patients who did not receive antiplatelet medication with regard to total blood loss, transfusion or 1-year mortality rates, according to recently published results. Researchers said the findings may indicate that patients can undergo urgent hip fracture surgery without drug cessation.

Researchers identified 176 patients who were 55 years of age or older with uncomplications hip fractures and underwent surgery within 48 hours after admission. Based on the preoperative medication regimen, 29 patients received aspirin and dipyridamole combined; 63 patients received aspirin alone; 29 patients received dipyridamole alone; and 56 patients did not receive antiplatelet medication. Investigators assessed total blood loss, transfusion rate and 1-year mortality rate.

Results showed the treatment groups were not significantly different with regard to total blood loss and 1-year mortality rate. Patients who received aspirin and dipyridamole combined preoperatively had increased intraoperative blood loss compared with patients who did not receive antiplatelet medication (mean 309 mL vs. 214 mL). After age, sex, Charlson Comorbidity Index and duration of hospital stay were adjusted, no differences were seen in hazard ratios among the groups. – by Monica Jaramillo

 

Disclosures: The authors report no relevant financial disclosures.