November 26, 2018
1 min read

Depression impacts subjective outcomes in patients who undergo TJA

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact

Significant improvements in patient-reported outcomes were seen in patients with depression who underwent total joint arthroplasty; however, overall improvements were based on patients’ mental health at the time of surgery, according to recently published results.

Researchers used a prospective, institutional joint registry to identify 469 patients who underwent primary total joint arthroplasty. The minimum follow-up was 1 year. The SF-12 mental component summary (SF-12 MCS) was used to measure baseline mental health. Based on the presence or absence of depression and on patients’ SF-12 MCS scores at time of surgery, investigators analyzed four cohorts. Primary outcomes included net change in SF-12 MCS, SF-12 physical component summary and WOMAC scores at 4 and 12 months postoperatively. Investigators performed univariate and mixed-effects model analyses to control for potential confounding factors.

Results showed patients with depression who had good baseline mental health achieved improvements similar to patients without depression. Investigators noted patients with poor baseline mental health achieved significant improvements in all patient-reported outcomes. However, the changes were greater for patients without depression. Patients with depression and poor baseline mental health did not cross the threshold for good mental health at the latest follow-up, even though they improved similarly in physical function compared with patients who did not have depression. –by Monica Jaramillo

Disclosures: The researchers report no relevant financial disclosures.