Crosslinked polyethylene associated with reduced revision rate for THA at long-term follow-up
In patients who underwent total hip arthroplasty for osteoarthritis, use of a crosslinked polyethylene bearing surface was linked to a significantly reduced revision rate at 16 years compared with conventional polyethylene, according to recently published results in The Journal of Bone and Joint Surgery.
“The Australian Orthopaedic Association National Joint Replacement Registry has demonstrated that in almost 200,000 primary THAs, the use of crosslinked polyethylene (XLPE) has resulted in a markedly reduced rate of revision at 16 years for all patients compared to the use of conventional polyethylene,” Richard de Steiger, MBBS, FRACS, FAOrthoA, told Healio.com/Orthopedics. “The study has demonstrated that longevity of THA is likely to be prolonged with the use of XLPE, with fewer patients undergoing revision surgery.”
de Steiger and colleagues performed an observational study of data from a national registry for all patients who underwent THA for osteoarthritis in Australia between 1999 and 2016. Results were compared between 41,171 THAs performed with conventional PE and 199,131 THAs performed with XLPE. Investigators also analyzed the impact of age, sex, femoral head size, method of acetabular and femoral component fixation, and reasons and types of revision. Kaplan-Meier estimates of survivorship were used to determine the time to first revision.
Results showed that after 6 months, XLPE correlated with a lower revision rate vs. conventional PE. Investigators noted the difference was more significant with time. In the conventional PE and XLPE groups, the 16-year cumulative revision percentage of primary THAs was 11.7% and 6.2%, respectively. After 9 years, the hazard ratio was 3.02. – by Monica Jaramillo
Disclosures: The researchers report no relevant financial disclosures.