October 05, 2017
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Patients with chronic kidney disease had increased risk for cardiovascular complications after TKA

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Patients with chronic kidney disease who underwent minimally invasive total knee arthroplasty had increased risks for blood transfusion, cardiovascular complications and 30-day readmission, according to results.

Researchers matched 205 patients with chronic kidney disease and a glomerular filtration rate of less than 60 mL per minute undergoing total knee arthroplasty (TKA) with 410 patients who did not have chronic kidney disease and a glomerular filtration rate of 60 mL per minute or greater. Researchers compared patient characteristics, comorbidities, preoperative hemoglobin, calculated total blood loss, transfusion rate, length of stay and postoperative complications between the two groups.

Results showed lower preoperative hemoglobin levels; higher preoperative comorbidities with cardiovascular disease, diabetes and gout; longer length of stay; and higher total blood loss among patients with chronic kidney disease. Chronic kidney disease was an independent risk factor for transfusions, cardiovascular complication and 30-day readmission, according to results of multivariate logistic regression. – by Casey Tingle

Disclosure s : The researchers report no relevant financial disclosures.