Poor diagnostic validity found with synovial PMMA spacer aspiration for detection of PJI
Synovial polymethylmethacrylate spacer aspiration had poor diagnostic validity in detecting persistent periprosthetic joint infection before total knee arthroplasty reimplantation, according to results.
To detect periprosthetic joint infection (PJI) in 73 patients who underwent second-stage septic revision total knee arthroplasty, researchers determined the sensitivity and specificity of the synovial polymethylmethacrylate-spacer joint aspiration and referenced this against microbiologic and histologic samples obtained at second-stage surgery.
Results showed synovial spacer aspiration detected persistent PJI in seven patients before second-stage surgery. Researchers noted false-negative results in 27 cases in reference to the intraoperative samples of the second-stage surgery. Bacterial species detected in four of the seven cases of culture-positive synovial spacer aspiration were in agreement with the bacterial species found during explantation. However, researchers found the other three cases of persistent PJI had bacterial species were different from those found during first-stage surgery. – by Casey Tingle
Disclosures: Preininger reports no relevant financial disclosures. Please see the full study for a list of all other authors’ relevant financial disclosures.