July 31, 2017
1 min read

Bone wax seen as effective for decreasing total blood loss after TKA

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Results from this study indicated that the use of bone wax in total knee arthroplasty safely and effectively reduced total blood loss and maintained hemoglobin levels higher than those of patients in a control group.

Researchers prospectively randomized 100 patients who underwent primary, unilateral total knee arthroplasty (TKA) with cement. Patients were randomized to either a study group that had 2.5g of bone wax applied to the bone and nail holes prior to tourniquet release or a control group that achieved hemostasis with electrocautery. The hemoglobin balance method was used to calculate total blood loss.

Results showed patients who received bone wax and those in the control group had similar preoperative serum hemoglobin levels. Investigators noted at 24 hours after TKA, the drop in serum hemoglobin levels in the bone wax group and the control group was 1.6 g/dL and 2.1 g/dL, respectively. After 72 hours, the drop in serum hemoglobin levels in the bone wax group and control group was 2.7 g/dL and 3.6 g/dL, respectively.

According to researchers, total blood loss after 72 hours in the bone wax group was 987.9 mL and 1,183.5 in the control group. At the 3-month follow-up, investigators saw no adverse events in patients who received bone wax. – by Monica Jaramillo

Disclosure : The researchers report no relevant financial disclosures.