Correlation seen between metal-ion levels and pseudotumors in asymptomatic, symptomatic THA patients
Results from this study demonstrated the presence of pseudotumors in both symptomatic patients and asymptomatic patients correlated with elevated serum levels of cobalt and cobalt/chromium.
Researchers performed a retrospective cross-sectional study of 97 patients who underwent total hip arthroplasty with a dual-taper modular femoral stem. Of these patients, 83 were categorized as either symptomatic or asymptomatic. Investigators evaluated these patients with metal artifact reduction sequence-MRI, serum metal-ion level measurements and the University of California, Los Angeles (UCLA) functional hip score.
Results showed a 15% prevalence of pseudotumors in asymptomatic patients. Investigators noted patients with a pseudotumor compared with those without a pseudotumor had a significantly higher median serum cobalt level and cobalt/chromium ratio. Researchers found no significant difference between symptomatic patients with pseudotumors and asymptomatic patients with pseudotumors regarding the serum cobalt level and the cobalt/chromium ratio. UCLA scores were similar in asymptomatic patients with a pseudotumor compared to patients without a pseudotumor. ‒ by Monica Jaramillo
Disclosures: Kwon reports he receives research support from Biomet, Stryker and Zimmer. Please see the full study for a list of all other authors’ relevant financial disclosures.