February 01, 2017
1 min read

Correlation seen between metal-ion levels and pseudotumors in asymptomatic, symptomatic THA patients

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Results from this study demonstrated the presence of pseudotumors in both symptomatic patients and asymptomatic patients correlated with elevated serum levels of cobalt and cobalt/chromium.

Researchers performed a retrospective cross-sectional study of 97 patients who underwent total hip arthroplasty with a dual-taper modular femoral stem. Of these patients, 83 were categorized as either symptomatic or asymptomatic. Investigators evaluated these patients with metal artifact reduction sequence-MRI, serum metal-ion level measurements and the University of California, Los Angeles (UCLA) functional hip score.

Results showed a 15% prevalence of pseudotumors in asymptomatic patients. Investigators noted patients with a pseudotumor compared with those without a pseudotumor had a significantly higher median serum cobalt level and cobalt/chromium ratio. Researchers found no significant difference between symptomatic patients with pseudotumors and asymptomatic patients with pseudotumors regarding the serum cobalt level and the cobalt/chromium ratio. UCLA scores were similar in asymptomatic patients with a pseudotumor compared to patients without a pseudotumor. by Monica Jaramillo


Disclosures: Kwon reports he receives research support from Biomet, Stryker and Zimmer. Please see the full study for a list of all other authors’ relevant financial disclosures.