October 27, 2014
1 min read

Autologous single-plug transplant a potential alternative for younger patients with osteochondral lesions

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According to recent study results, autologous single-plug osteochondral transplantation could be a good treatment option for osteochondral knee cartilage lesions of small and medium size in younger patients.

Researchers evaluated 15 patients with an average age of 30.2 years who underwent autologous single-plug osteochondral transplantation to treat grade III or IV osteochondral knee lesions. Metrics analyzed included Lysholm, IKDC subjective and Tegner values. Average follow-up was 17.5 years.

Significant improvement was observed in IKDC subjective scores from baseline to final follow-up (34.5 vs. 66.3), as well as in Lysholm scores from baseline to final follow-up (47.8 vs. 79.8), according to the researchers.

Although Tegner values showed similar significant improvement at final follow-up from baseline levels (5.2 vs. 4.1), the difference between preinjury and postoperative values shows patients did not return to preinjury sport activity levels, according to the researchers.

Of the four patients who were determined to have treatment failure, three occurred at mid- to long-term follow-up.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.