November 20, 2015
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Obstructive sleep apnea increases risk for glaucoma

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Researchers found that obstructive sleep apnea is a risk factor for glaucoma, according to a recently published study.

Shulin Liu, MD, and colleagues reported in the Journal of Glaucoma that they used a meta-analysis and literature review to identify six primary studies involving nearly 2.3 million participants.

The paper outlined the inclusion criteria: obstructive sleep apnea (OSA) was diagnosed by physicians, polysomnography or respiratory polygraphy; the researchers selected only cohort or case-control studies; and the relationship between OSA and risk for glaucoma in terms of odds ratio, relative risk and hazard risk was available.

Compared with the non-OSA group, OSA was associated with more frequent glaucoma, the authors said. Chinese OSA patients had a higher risk of developing glaucoma than people in other countries.

The researchers also suggested that female and younger OSA patients may have a higher risk for glaucoma.

The cohort studies exhibited that OSA was associated with a 1.43-fold increased risk of glaucoma, and case-control studies showed a 2.46-fold increased risk, according to researchers.

Researchers also found a 72% increase in the risk when the endpoint contained greater than one type of glaucoma.

The researchers concluded: “On the basis of our meta-analysis of three case-control and three cohort studies, OSA was a risk factor for glaucoma, especially in China, but may not increase the risk of OAG.” – by Abigail Sutton

Disclosure: The researchers reported no relevant financial disclosures.