Biography/Disclosures
Biography: Singh is a staff surgeon at the Cole Eye Institute, Cleveland Clinic and Associate Professor of Ophthalmology at the Lerner College of Medicine in Cleveland Ohio. He also currently serves as the medical director of informatics at the Cleveland Clinic.
March 20, 2020
1 min read
Save

BLOG: Can we use fundus autofluorescence to differentiate retinoschisis from retinal detachments?

Biography/Disclosures
Biography: Singh is a staff surgeon at the Cole Eye Institute, Cleveland Clinic and Associate Professor of Ophthalmology at the Lerner College of Medicine in Cleveland Ohio. He also currently serves as the medical director of informatics at the Cleveland Clinic.
You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Retinoschisis is a nonprogressive degenerative splitting of the neurosensory retina, most often at the outer plexiform layer.

On clinical examination, retinoschisis (RS) can sometimes prove difficult to distinguish from retinal detachments (RD), specifically in patients with chronic detachments that also may present with a smooth surface similar to that seen in RS. In addition, some cases of RS can be complicated by a progressive RD (retinoschisis-detachment [RS/RD]) if there are both inner and outer layer breaks in the retina. It is important to differentiate RS from an RD or RS/RD because management differs.

A modality that has only recently been evaluated as a possible tool for the differentiation of RS from RD or RS/RD is widefield fundus autofluorescence (WF-FAF). Two recent reports in the literature suggest that WF-FAF can differentiate these lesions based upon the pattern seen. We recently conducted our own evaluation at the Cole Eye Institute, Cleveland Clinic, to corroborate these findings. We found no statistically significant correlation between the autofluorescence pattern and the type of retinal abnormality. In fact, we found multiple patterns of WF-FAF within patients with RS and RD.

You can read more at https://journals.sagepub.com/doi/10.1177/2474126420907020.

 

Like what you are reading? Follow me on Instagram, Facebook and Twitter @drrishisingh.

 

Disclosure: Singh reports he is a consultant to Zeiss, Novartis, Regeneron, Genentech and Alcon and receives grant support from Apellis and Graybug.