American Society of Retina Specialists Meeting
American Society of Retina Specialists Meeting
July 30, 2019
1 min read

Removing membrane between Argus II, retina may restore normal function of device

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Fabio Patelli

CHICAGO — The histological characteristics of an epiretinal membrane that had formed between an Argus II retinal prosthesis and a patient’s retina were described here.

“The fibrosis seems to be a reaction from the foreign body. We found iron in the tissue,” Fabio Patelli, MD, said at the American Society of Retina Specialists annual meeting.

Patelli and colleagues removed an epiretinal membrane that developed between the Argus II (Second Sight Medical Products) and the retina. The membrane was composed of spindle cell elements similar to fibroblasts, mixed with an inflammatory infiltrate, he said.

Patelli said the membrane showed electron-dense round particles resembling metallic deposits at a cytoplasmic level.

“Iron particles were visible as perinuclear intracellular deposits,” he said.

Before the removal of the membrane, the device was operating at a low level. One month after surgery to remove the membrane, functioning was restored to normal operating levels, he said. by Robert Linnehan



Patelli F. Epiretinal membrane removal in an Argus II implanted eye: histological characteristics and functional results. Presented at: American Society of Retina Specialists annual meeting; July 27-30, 2019; Chicago.

Disclosure: Patelli reports no relevant financial disclosures.