November 06, 2017
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No changes seen in surgical time, corneal edema with hydrogel sealant

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Eyes with hydrogel ocular sealant used to secure clear corneal incisions during cataract surgery experienced no statistical differences in wound leaks, total surgical time or corneal edema compared with non-sealant eyes.

Researchers retrospectively reviewed 90 eyes of 45 cataract surgery patients in a 1:1 matched cohort of ReSure hydrogel ocular sealant (Ocular Therapeutix) and non-sealant.

The difference in surgical time for sealant eyes and non-sealant eyes was not statistically significant. Additionally, there were no statistically significant differences between non-sealant eyes and sealant eyes regarding IOP, odds of clinically noted corneal edema or rate of foreign body sensation.

“The findings indicate that the ReSure hydrogel ocular sealant did not significantly alter surgical characteristics or patient symptomatology when used in routine or complex cataract surgeries. The findings are relevant for surgeons concerned with surgical efficiency and also indicate that patient counseling about sealant use for wound closure might not be warranted,” the researchers wrote.

No wound leaks were found 1 day postoperatively in any eyes, and two cases out of 45 had displaced hydrogel ocular sealant. – by Robert Linnehan

Disclosures: Nallasamy reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures.