Early vitrectomy may decrease time with vision loss in eyes with vitreous hemorrhage
Immediate vitrectomy with endolaser may reduce the amount of time a patient has low vision and the need for adjunctive panretinal photocoagulation in eyes treated for vitreous hemorrhage associated with proliferative diabetic retinopathy, according to a study.
The retrospective study included 46 eyes; 17 eyes underwent vitrectomy within 30 days of initial presentation and 29 eyes underwent vitrectomy after 30 days.
Average time to vitrectomy was 14.8 days in the immediate vitrectomy group and 629.6 days in the delayed vitrectomy group.
Preoperatively, the area under the vision curve was 276.1 logMAR*time in the delayed group and 165.7 logMAR*time in the immediate group; the between-group difference was statistically significant (P < .0001). Postoperatively, the area under the vision curve was 163.6 logMAR*time and 122 logMAR*time, respectively. The postoperative between-group difference was not significant, but both improvements were significant (P < .0001 and P = .0001, respectively).
Both groups needed significantly less adjunctive PRP after vitrectomy (P < .05). Nine eyes (52.9%) in the immediate group and 21 eyes (72.4%) in the delayed group underwent PRP before vitrectomy. Three (17.6%) in the immediate group and one eye (3.2%) in the delayed group underwent PRP after vitrectomy.
Preoperative visual acuity was 1.86 in the immediate group and 1.71 in the delayed group. Postoperative visual acuity at 6 months or final follow-up was 0.35 in the immediate group and 0.31 in the delayed group; the improvements were statistically significant in both groups (P = .002 and P < .0001, respectively). The differences between the groups were not significant before or after surgery. – by Matt Hasson
Disclosure: The authors report no relevant financial disclosures.