August 26, 2014
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Canaloplasty poses risk of Descemet's membrane detachment

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Canaloplasty was associated with a slight risk of Descemet’s membrane detachment, with or without intracorneal hemorrhage, according to study findings.

The retrospective study included 162 eyes of 115 patients who underwent canaloplasty. Researchers evaluated visual acuity, IOP, number of glaucoma medications and incidence of Descemet’s membrane detachment (DMD) for up to 1 year.

DMD was identified in 12 of 162 eyes (7.4%); all 12 eyes were followed for at least 12 months. Of the 150 eyes that did not develop DMD, 132 were followed for at least 12 months.

Visual acuity, IOP and number of glaucoma medications were similar in both the DMD group and non-DMD group at baseline and at 12-month follow-up, according to the researchers.

Results showed that 10 DMDs (83%) involved the inferior quadrants and were smaller than 3 mm. Seven of 12 eyes with DMD (58%) had intracorneal hemorrhage; five of the 12 eyes (42%) developed DMD with intracorneal viscoelastic alone.

DMD with viscoelastic alone resolved spontaneously within 1 month, with no sequelae. In three eyes that developed intracorneal hemorrhage, the DMD and hemorrhage resolved spontaneously within 6 weeks.

Two patients had large detachments measuring 5 mm to 6 mm and extending into the visual axis.

DMD resolved with or without drainage. One patient developed corneal decompensation and required penetrating keratoplasty.

Disclosure: Ayyala is a consultant for iScience International. The other authors have no relevant financial disclosures.