July 29, 2014
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PK, DSAEK offer similar graft survival rates regardless of glaucoma therapy

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Penetrating keratoplasty and Descemet’s stripping automated endothelial keratoplasty had comparable graft survival rates in eyes without glaucoma management and in eyes with comparable glaucoma management, according to a study.

Researchers performed a retrospective chart review for 57 eyes that underwent PK and 156 eyes that underwent DSAEK. Patients’ eyes were categorized as having no glaucoma treatment, medical therapy only or surgical intervention.

Five-year Kaplan-Meier graft survival rate in eyes with no glaucoma treatment was 94.7% after PK and 93.8% after DSAEK. In eyes that received medical therapy only, the 5-year Kaplan-Meier graft survival rate was 93.8% after PK and 96.3% after DSAEK.

Graft survival was found to be significantly worse in eyes that underwent surgical intervention for glaucoma, according to the researchers, with survival rates of 56.8% and 50% after PK and DSAEK, respectively.

Disclosure: The authors have no relevant financial disclosures.