July 15, 2014
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Accelerated corneal collagen cross-linking effective for stabilizing keratoconus

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In patients with mild to moderate keratoconus, accelerated corneal collagen cross-linking is effective for stabilizing topographic parameters after 12 months, according to study findings.

Researchers retrospectively reviewed data from 16 eyes of 14 patients with mild to moderate keratoconus-affected eyes who had reached 6 and 12 months of follow-up. The researchers extracted and analyzed uncorrected distance visual acuity, manifest refraction, corrected distance visual acuity and computerized corneal topography data preoperatively and after corneal cross-linking.

At 6 and 12 months, no statistically significant differences were found in mean corrected distance visual acuity, mean refractive cylinder or mean manifest refraction spherical equivalent, according to the researchers. Ten of 16 eyes either gained logMAR lines or remained stable in CDVA at 6 months, and 13 of 16 eyes gained logMAR lines or remained stable in CDVA at 12 months.

No postoperative complications were reported in the study.

Disclosure: The authors have no relevant financial disclosures.