May 23, 2014
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CDVA lost in short-term, regained at 1 year after small-incision lenticule extraction

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Small-incision lenticule extraction showed an acceptable safety profile despite a relatively high percentage of eyes that lost corrected distance visual acuity at 3 months, according to a study.

The clinical-control cohort study included 1,800 eyes of 922 patients who underwent small-incision lenticule extraction (smile) in both eyes. Three-month follow-up included 1,574 eyes.

Postoperative corrected distance visual acuity (CDVA) was the same or better than preoperative CDVA in 1,346 eyes (86%) by 3-month follow-up. CDVA improved by two or more lines in 54 eyes (3.4%) but decreased by two or more lines in 24 eyes (1.5%). However, CDVA rebounded to within one line of the preoperative value in all eyes at an average of 18 months, according to the researchers.

Average CDVA improved significantly, from −0.03 preoperatively to −0.05 postoperatively (P < .001).

Postoperative complications included trace haze in 8% of eyes, epithelial dryness in 5%, interface inflammation secondary to central abrasion in 0.3% and minor interface infiltrates in 0.3%. The complications affected CDVA in one case.

Disclosure: Sven Asp, MD, DMSci, and Jesper Hjortdal, MD, DMSci, received travel reimbursement from Carl Zeiss Meditec.