March 31, 2014
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SLT lowers IOP, has small risk of adverse effects in eyes with moderate POAG

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Selective laser trabeculoplasty significantly reduces IOP in eyes with primary open-angle glaucoma without inducing adverse effects, according to a study.

The short-term prospective study included 64 eyes with moderate POAG. Medical treatment was not successful in these eyes, which had not been treated previously with laser or filtering surgery. The same medical treatment was continued after SLT.

Anti-inflammatory treatment was not given preoperatively or postoperatively.

Mean preoperative IOP was 19.1 mm Hg. After SLT, mean IOP were 12.9 mm Hg at 24 hours, 13.2 mm Hg at 2 weeks, 14.1 mm Hg at 6 weeks and 13.9 mm Hg at 3 months (all P < .001).

The study authors observed no significant increase in mean retinal thickness and no signs of inflammation in the anterior chamber or vitreous.

“Further studies need to be conducted to detect inflammatory signs in pseudoexfoliative or pigmentary glaucoma following SLT,” they said.

Disclosure: The authors have no relevant financial disclosures.