March 19, 2014
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Eyes with uveitic glaucoma more prone to surgical failure after trabeculectomy

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Surgical failures are more likely in eyes with uveitic glaucoma than in eyes with primary open-angle glaucoma after trabeculectomy with mitomycin C, according to a study.

Furthermore, uveitic glaucoma eyes are more likely to require additional cataract surgery and less likely to maintain IOP reduction.

The retrospective, consecutive, comparative cohort study included 101 eyes with uveitic glaucoma and 103 eyes with primary open-angle glaucoma that underwent trabeculectomy with MMC.

Nineteen (18.8%) uveitic glaucoma eyes and 10 (9.7%) primary open-angle glaucoma eyes were surgical failures. Thirty (29.7%) uveitic glaucoma eyes and eight (7.8%) primary open-angle glaucoma eyes needed additional cataract surgery after trabeculectomy due to cataract progression.

Granulomatous uveitis was an important factor leading to surgical failures (P = .0106), as was previous cataract surgery (P = .0344).

After trabeculectomy with MMC, eyes with nongranulomatous uveitis had a success rate of 94.4% at 1 year and 85.6% at 2 years, and the success rate for eyes with granulomatous uveitis was 72.4% at 1 year and 54.3% at 2 years.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.