February 26, 2014
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Glaucoma filtration device, trabeculectomy similarly successful at 2 years

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A glaucoma filtration device and trabeculectomy yielded similar clinical and visual results at 2 years, according to a study.

The prospective randomized multicenter trial included 120 eyes of 120 patients; 59 eyes were treated with the Ex-Press device (Alcon) and 61 eyes underwent trabeculectomy.

Patients in both groups were followed for 2 years after surgery. Surgical success was defined as IOP of 5 mm Hg to 18 mm Hg with or without medications and without additional glaucoma surgery.

Baseline logMAR visual acuity was 0.3 in the Ex-Press group and 0.25 in the trabeculectomy group. Postoperative visual acuity was 0.28 in the Ex-Press group and 0.37 in the trabeculectomy group at 2 years.

Mean visual acuity decreased significantly in both groups at 1 day but recovered at 1 month in the Ex-Press group and 3 months in the trabeculectomy group.

Mean IOP decreased from 25.1 mm Hg at baseline to 14.7 mm Hg in the Ex-Press group and from 26.4 mm Hg to 14.6 mm Hg in the trabeculectomy group. The decrease in IOP was statistically significant in both groups (P < .001).
Medication use decreased significantly in both groups at 2 years (P < .001).

The 2-year success rate was 83% in the Ex-Press group and 79% in the trabeculectomy group.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.