February 25, 2014
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Cataract surgery linked to changes in choroidal thickness, study finds

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Cataract surgery was associated with changes in choroidal thickness, with axial length and IOP being critical in evaluating those changes, according to a study.

“The choroid may be involved in the pathogenesis of various ocular diseases,” the study authors said. “It has been suggested that cataract surgery is associated with the onset of AMD.”

The prospective study included 100 eyes of 100 patients with a mean age of 72.5 years and no other ocular disease who underwent cataract surgery. A control group included 20 eyes of 20 age-matched subjects.

Using enhanced-depth imaging optical coherence tomography, investigators evaluated changes over time in corrected distance visual acuity (CDVA), IOP, axial length and choroidal thickness preoperatively.

IOP in the study group decreased significantly at 3 weeks, 3 months and 6 months postoperatively.

Choroidal thickness increased significantly in the foveal and inferior regions for the duration of follow-up. It increased in the nasal region at 3 days, 1 week and 6 months, in the temporal region at 1 week and in the superior region at 6 months. The changes correlated negatively with early postoperative changes in IOP. Changes in choroidal thickness had a negative correlation with axial length in all regions.

Age, CDVA, preoperative IOP and surgical time correlated insignificantly with changes in choroidal thickness.

Mean IOP and choroidal thickness remained unchanged in the control group, the authors said.

Disclosure: The study authors report no relevant financial disclosures.