February 24, 2014
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Pathologic myopia associated with higher OSDI scores, lower TBUT

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Patients with pathologic myopia experienced more severe Ocular Surface Disease Index symptoms and faster tear film breakup times than controls, according to a study.

The study compared 45 patients with pathologic myopia with 44 healthy individuals. Researchers defined pathologic myopia as spherical equivalent (SE) refractive errors greater than 6 D and axial globe length (AL) of more than 26.5 mm.

No statistically significant difference between groups was seen in corneal staining or in Schirmer's 1 test scores, both with and without anesthesia, but SE, keratometry, AL, tear breakup time (TBUT) and OSDI scores were each statistically significantly different between groups (P < .001).

Mean TBUT was 7.2 seconds in the myopic group and 13.6 seconds in the control group. Sixty percent of patients in the pathologic myopia group had severe OSDI symptoms, whereas 75% of patients in the control group had no ocular symptoms.

"This supports the relationship between pathological myopia with tantalic [dry eye syndrome],” a condition that occurs in some abnormalities that lead to increased eyelid space, according to the authors.

Disclosure: The study authors report no relevant financial disclosures.