September 20, 2013
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Fluid-gas exchange an effective alternative for open macular holes after vitrectomy

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Outpatient fluid-gas exchange was an effective alternative for eyes with open macular holes after vitrectomy, a study found.

Thirty-six patients with primary failed closure or reopened macular holes after vitrectomy were included in the institutional study.

Anatomic success was attained in 32 eyes (89%) between 1 and 3 weeks following fluid-gas exchange. Type 1 closure was attained in 22 eyes (61%), type 2 closure was attained in 10 eyes (28%) and no closure was attained in four eyes (11%).

LogMAR best corrected visual acuity for type 1 closure improved from 1.66 to 0.84; the gain was significant (P < .001). LogMAR BCVA for type 2 closure improved from 1.77 to 1.52, which was also significant (P = .05).

All eyes that did not attain hole closure had a stage IV macular hole and an average hole size greater than 1000 µm.

Following fluid-gas exchange, retinal detachment was reported in two eyes (6%), elevated IOP was reported in three eyes (8%) and cataracts developed in 34 eyes (94%); however, all eyes were corrected.

Disclosure: Chi-Chun Lai is a consultant of Allergan, Bayer and Novartis. The remaining authors have no relevant financial disclosures.