American Society of Retina Specialists Meeting

American Society of Retina Specialists Meeting

August 28, 2013
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Endogenous endophthalmitis associated with decreased visual acuity

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TORONTO — Despite early management, poor visual acuity outcomes are associated with endogenous endophthalmitis caused by yeast, according to a poster presentation.

Patients who underwent recent remote surgery were the most common to incur endogenous fungal endophthalmitis, Jayanth Sridhar, MD, and colleagues, said in a poster presented at the American Society of Retina Specialists meeting.

Microbiologic records of Bascom Palmer Eye Institute patients were retrospectively reviewed for endogenous endophthalmitis caused by yeast. Medical records were analyzed for clinical presentation, management strategies, visual acuity and outcomes.

Fifty-one eyes of 39 patients were included in the study with a mean follow-up of 16.7 months. The most common symptom was decreased vision (38/51 eyes, 74.5%), followed by redness (23/51, 45.1%) and pain (20/51, 39.2%).

Risk factors included recent remote surgery (12/39, 30.8%), cancer (9/39, 23.1%), intravenous drug abuse, diabetes mellitus, and cardiac, respiratory or gastrointestinal disease. The most common organism cultured was Candida albicans (86.2%) and initial treatment was combination of medical and surgical for 21 eyes (41.1%). Retinal detachment during treatment occurred in 15 eyes (29.4%).

Visual acuity was 20/200 or better in 21 eyes on presentation (41.2%) and in 31 eyes (60.8%) at the last follow-up, the study authors said.

Disclosure: The authors report no relevant financial disclosures.