August 16, 2013
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HD-OCT thickness maps best confirm RNFL defects in eyes with early glaucoma

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Thickness maps generated with high-definition spectral-domain optical coherence tomography proved more useful than other maps in identifying retinal nerve fiber layer defects in glaucomatous eyes, according to a study.

Investigators evaluated the accuracy of clock-hour, deviation and thickness maps created with the Cirrus HD-OCT (Carl Zeiss Meditec) in detecting retinal nerve fiber layer (RNFL) defects previously identified in red-free fundus photographs.

The study included 295 eyes with early glaucomatous RNFL defects; a control group comprised 200 healthy, age-matched eyes. Mean patient age was 50.6 years in the glaucoma group and 49.7 years in the control group.

Visual acuity, refractive error, IOP, slit lamp biomicroscopy, fundus photos, visual fields and RNFL measurements were assessed.

Among the 295 defects observed in glaucomatous eyes, 83 defects were misidentified in the clock-hour map, 27 were misidentified in the deviation map and none were misidentified in the thickness map.

In the control group, 25 defects were misidentified in the clock hour map, 30 were misidentified in the deviation map and 12 were misidentified in the thickness map.

Disclosure: The study authors report no relevant financial disclosures.

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