August 15, 2013
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Intact ELMs, normal FAF patterns help predict BCVA after macular hole repair

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Intact external limiting membranes and normal hypofluorescence patterns most accurately predicted postoperative visual acuity after vitrectomy for idiopathic macular holes, according to a study.

The retrospective study included 77 eyes of 75 patients with an average age of 57.8 years who underwent vitrectomy for idiopathic macular holes.

Investigators performed fundus autofluorescence (FAF) imaging and spectral-domain optical coherence tomography for up to 12 months postoperatively. The primary outcome measures were macular hole size, FAF patterns, OCT retinal outer segment and best corrected visual acuity.

Thirty-seven eyes had intact external limiting membranes (ELMs); 12 of those eyes had normal hypofluorescence, six had homogenous hyperfluoresence and 19 had patchy hyperfluorescence.

BCVA was significantly better in patients with intact ELMs than in patients without intact ELMs (P < .001). Patients who had both intact ELMs and normal FAF patterns (P = .011) also had better BCVA.

Disclosure: The study authors report no relevant financial disclosures.