August 09, 2013
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Macular hole closure with ILM peeling linked to progressive macular thinning

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Macular hole closure with internal limiting membrane peeling resulted in progressive macular thinning up to 2 years after surgery, according to a study.

The prospective, interventional case study included 24 eyes of 24 patients with a mean age of 65.5 years who underwent macular hole closure with internal limiting membrane peeling. Spectral-domain optical coherence tomography was used to measure regional retinal thickness in the macular area.

Patients were evaluated preoperatively and at 1, 2, 3, 6, 9, 12 and 24 months postoperatively.

Significant thinning was seen in the inner temporal, superior, inferior and nasal sectors at 1 month (P ≤ 0.0001–0.020). Thinning progressed in all inner sectors except the inner nasal sector for 2 years.

Thickness in the four outer sectors increased at 1 month and subsequently decreased up to 2 years.

No patients lost more than two lines of best corrected visual acuity, the authors said.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.

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