Increased excavation, neuroretinal rim thinning common in optic disc progression
Increased excavation and neuroretinal rim thinning, particularly in the inferotemporal quadrant, were the most common features of optic disc progression, according to a study.
The study included 336 eyes of 168 patients with either high-risk ocular hypertension or early glaucoma who underwent optic disc photography through dilated pupils at baseline and annual follow-up appointments.
Optic disc progression occurred in 92 eyes after a median of 6.1 years. Eighty-nine percent of the eyes demonstrated excavation, 54% demonstrated neuroretinal rim thinning, and 16% demonstrated notching.
Two or more features of optic disc progression were present in 56% of eyes.
Thirty percent of eyes experienced progression in more than one location; progression was most common in the inferotemporal quadrant.
Early detection of optic disc changes may allow physicians to adjust patients’ therapy to avoid visual field loss and worsening of vision-associated quality of life, the study authors said.