July 05, 2013
1 min read

Omega-3 fatty acids may reduce progression of geographic atrophy

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Increased dietary intake of omega-3 fatty acids may be associated with reduced risk of geographic atrophy, according to a study.

“Our study of progression differs from [other] studies by including up to 12 years of follow-up, adjusting for several genetic variants, testing for gene-nutrient interactions and including all nonadvanced eyes at baseline in the analyses,” the study authors said.

The prospective cohort study included 2,531 patients from AREDS (the Age-Related Eye Disease Study). Among these patients, 525 eyes progressed to geographic atrophy. The authors collected demographic, behavioral and dietary information from questionnaires at baseline.

 Individuals controlled for age-related macular degeneration grade, sex, age, AREDS treatment, education, smoking, body mass index and caloric intake saw a reduction in risk of geographic atrophy progression with intake of omega-3. Patients with these factors and ARMS2/HTRA1 homozygous risk genotype also saw a significant trend in the reduction of progression (P = .01), according to the study.

Eating one or more 3-ounce serving per week of fish high in omega-3 fatty acids, such as salmon, mackerel or sardines, may reduce progression of geographic atrophy, the authors said.