June 19, 2013
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Early anterior inflammation in diabetic eyes relates to anterior capsule contraction

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Anterior inflammation 1 week after cataract surgery contributes to contraction of the anterior capsule opening in eyes of patients with diabetes, according to a study.

The case-control study was comprised of 60 eyes with type 2 diabetes mellitus and 35 eyes without diabetes mellitus that had undergone cataract surgery. Thirty-one of the 60 diabetic eyes had no diabetic retinopathy and 29 had nonproliferative diabetic retinopathy.

At 1 day, 1 week, 1 month and 3 months after cataract surgery, the anterior capsule opening was measured with the EAS-1000 (Nidek), and aqueous flare intensity was measured with a laser flare-cell meter.

In diabetic retinopathy eyes, anterior capsule contraction was higher than in eyes without diabetes mellitus and diabetic retinopathy at 1 week, 1 month and 3 months (P < .01). Aqueous flare intensity was greater in diabetic retinopathy eyes than in eyes without diabetes mellitus and diabetic retinopathy at 1 day, 1 week and 1 month (P < .01)

The correlation between aqueous flare intensity at 1 week and percentage reduction in the anterior capsule opening at 3 months suggests that the early postop anterior inflammation is related to the progression of anterior capsule contraction in patients with diabetes, the authors said.