Early anterior inflammation in diabetic eyes relates to anterior capsule contraction
Anterior inflammation 1 week after cataract surgery contributes to contraction of the anterior capsule opening in eyes of patients with diabetes, according to a study.
The case-control study was comprised of 60 eyes with type 2 diabetes mellitus and 35 eyes without diabetes mellitus that had undergone cataract surgery. Thirty-one of the 60 diabetic eyes had no diabetic retinopathy and 29 had nonproliferative diabetic retinopathy.
At 1 day, 1 week, 1 month and 3 months after cataract surgery, the anterior capsule opening was measured with the EAS-1000 (Nidek), and aqueous flare intensity was measured with a laser flare-cell meter.
In diabetic retinopathy eyes, anterior capsule contraction was higher than in eyes without diabetes mellitus and diabetic retinopathy at 1 week, 1 month and 3 months (P < .01). Aqueous flare intensity was greater in diabetic retinopathy eyes than in eyes without diabetes mellitus and diabetic retinopathy at 1 day, 1 week and 1 month (P < .01)
The correlation between aqueous flare intensity at 1 week and percentage reduction in the anterior capsule opening at 3 months suggests that the early postop anterior inflammation is related to the progression of anterior capsule contraction in patients with diabetes, the authors said.