August 02, 2012
1 min read

Similar visual function seen with different IOL materials at 10 years

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Eyes implanted with acrylic, silicone and PMMA IOLs had similar visual function and higher-order aberrations 10 years after cataract surgery, a study found.

“These results indicate that surface scattering and glistenings do not markedly affect the optical performance of the eye,” the study authors said.

The case-control study included 105 patients who underwent phacoemulsification. Three patients missed some examinations and were excluded from the analysis.

Thirty-five eyes were implanted with a hydrophobic acrylic IOL (AcrySof, Alcon), 32 eyes were fitted with silicone IOLs (SI30NB or SI40NB, Abbott Medical Optics) and 35 eyes received PMMA IOLs (MZ60BD, Alcon, or UV25T, UV22 or UV60SB, Menicon) 10 years previously.

Mean patient age at the time of the investigation was 75.4 years.

All eyes underwent evaluation of visual acuity, wavefront aberrometry, biomicroscopy and keratometry. Scheimpflug imaging was used to assess posterior capsule opacification and light scatter at the optic surface and inner optic.

Study results showed that the acrylic IOL group had a significantly higher mean scattering light intensity of the surface and interior matrix than the silicone and PMMA IOL groups (P < .0001). However, scattering light intensity of the surface and internal matrix did not correspond with visual function or optical aberrations in the acrylic IOL group.

All three IOL groups had similar mean uncorrected visual acuity, photopic and mesopic contrast visual acuity and glare visual acuity, and higher-order aberrations. However, the acrylic IOL group had significantly better mean corrected visual acuity than the other groups (P = .0003).

Posterior capsule opacification rates were similarly low in all three groups, the authors said.