Noninvasive techniques promising for imaging diabetic macular edema
FORT LAUDERDALE, Fla. — A noninvasive modality that shows extension and pattern of diabetic macular edema may replace fluorescein angiography in imaging these patients, a poster presenter told Ocular Surgery News.
"The combined use of noninvasive imaging techniques can improve the diagnostic interpretation of different aspects of DME, probably avoiding invasive tests," Stela Vujosevic, MD, and colleagues said in a poster presented at the Association for Research in Vision and Ophthalmology meeting.
In a prospective, comparative series of 263 eyes with any stage of diabetic retinopathy, the "pseudo-3D" modality of scanning laser ophthalmoscope in the retromode (RM-SLO), color fundus photos, time-domain optical coherence tomography (OCT), fundus autofluorescence (FAF) and fundus fluorescein angiography (FFA) were all done on the same day to evaluate lesions independently by two masked retina specialists.
"For lesions graded as elevations (leaking microaneurysms and drusen), theagreement was perfect vs. FFA," the authors said.
Agreement regarding presence of DME was good among RM-SLO, OCT, FFA and FAF; for cystoid pattern, agreement was "almost perfect" for all imaging modalities, as it was for presence of subfoveal neuroretinal detachment between RM-SLO and OCT.
Noninvasive imaging with RM-SLO, an already available modality that has a noninvasive nature and the ability to measure height and extension of disease, may replace more invasive methods such as FFA for imaging diabetic macular edema, Dr. Vujosevic said.
- Disclosure: Dr. Vujosevic has no relevant financial disclosures.